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What is Haemoglobin?


By rakeshdhanya - Posted on 19 December 2008

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Haemoglobin is the iron-containing protein attached to red blood cells that transports oxygen from the lungs to the rest of the body. Haemoglobin bonds with oxygen in the lungs, exchanges it for carbon dioxide at cellular level, and then transports the carbon dioxide back to the lungs to be exhaled.Whether haemoglobin binds with oxygen or carbon dioxide depends on the relative concentration of each around the red blood cell. When it reaches the oxygen-rich lungs, it releases the less-abundant carbon dioxide to bind with oxygen; when it goes back out into the body where cells are producing carbon dioxide, it releases the oxygen and binds with carbon dioxide.Haemoglobin abnormalities result in very serious hereditary diseases, such as sickle-cell anaemia and thalassemia.Haemoglobin is made up of four subunits, with a haem (iron-containing) group in each for oxygen binding. There are slightly different haemoglobins in adults when compared to children and foetuses.The level of haemoglobin is measured to check the oxygen carrying capacity of the blood. The low oxygen carrying capacity of the blood leads to the symptoms of anaemia (low level of haemoglobin).